Imbalanced chordal force distribution causes acute ischemic mitral regurgitation: Mechanistic insights from chordae tendineae force measurements in pigs
نویسندگان
چکیده
منابع مشابه
Acute mitral regurgitation in pregnancy due to ruptured chordae tendineae.
Rupture of chordae tendineae resulting in acute mitral regurgitation has previously been described following rheumatic fever, subacute bacterial endocarditis, blunt chest trauma, and in Marfan's syndrome. Chordae may rupture spontaneously in older patients, producing a characteristic clinical syndrome, but such 'idiopathic' rupture is exceptional before the age of 50. This paper reports the occ...
متن کاملHemodynamics in ruptured chordae tendineae and chronic rheumatic mitral regurgitation.
Twenty-five patients with proven ruptured mitral chordae tendineae and 25 patients with chronic rheumatic mitral regurgitation were studied with quantitative biplane left-heart angiocardiography. Compared to the rheumatic patients, the ruptured chordae group had strikingly smaller left atrial maximum volume (mean: 119 + 47 vs 267 + 131 mI/M2 mean) and less compliant left atrium (mean: 1.61 1.52...
متن کاملRuptured Chordae Tendineae and Chronic Rheumatic Mitral Regurgitation
Twenty-five patients with proven ruptured mitral chordae tendineae and 25 patients with chronic rheumatic mitral regurgitation were studied with quantitative biplane left-heart angiocardiography. Compared to the rheumatic patients, the ruptured chordae group had strikingly smaller left atrial maximum volume (mean: 119 + 47 vs 267 + 131 mI/M2 mean) and less compliant left atrium (mean: 1.61 1.52...
متن کاملChordal force distribution determines systolic mitral leaflet configuration and severity of functional mitral regurgitation.
OBJECTIVES The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these have to comply with the chordal force distribution defined by the chordal coap...
متن کاملRuptured mitral chordae tendineae.
AMONG THE LESIONS responsible for insufficiency of the mitral valve is rupture of the chordae tendineae. It is our purpose to describe the significant clinical and pathologic findings in 20 cases of insufficiency of the mitral valve due to rupture of the chordae tendineae. This report is based on those cases in which ruptured mitral chordae tendineae were found at necropsy at the Mayo Clinic du...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2005
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2004.07.044